Tooth Abnormalities and Occlusal Disorders in Individuals with Frontonasal Dysplasia

• Published in: The Cleft palate-craniofacial journal Vol. 54; no. 3; pp. 304 - 308
• Main Authors: Dainezi, Vanessa Benetello, Das Neves, Lucimara Teixeira, Da Silva Dalben, Gisele, Gomide, Marcia Ribeiro
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01-05-2017; SAGE PUBLICATIONS, INC
• Subjects: Adolescent; Birth defects; Brazil - epidemiology; Child; Craniofacial Abnormalities - diagnostic imaging; Craniofacial Abnormalities - epidemiology; Cross-Sectional Studies; Dentistry; Dentists; Face - abnormalities; Face - diagnostic imaging; Female; Genetic counseling; Humans; Intellectual disabilities; Male; Malocclusion - diagnostic imaging; Malocclusion - epidemiology; Mutation; Orthodontics; Pediatrics; Prevalence; Radiography, Panoramic; Rehabilitation; Teeth; Tooth Abnormalities - diagnostic imaging; Tooth Abnormalities - epidemiology; Brazil; tooth abnormalities; craniofacial abnormalities; median cleft face syndrome; frontonasal dysplasia
• ISSN: 1055-6656; 1545-1569
• DOI: 10.1597/15-286

Objective
Frontonasal dysplasia is a rare developmental defect of the midface, and little is known about the dental involvement in individuals with this condition. This study investigated tooth abnormalities and occlusal disorders in individuals with frontonasal dysplasia.
Design
Cross-sectional.
Setting
Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, Brazil.
Interventions
Clinical oral examination, analysis of patient records, and panoramic radiographs.
Participants
A total of 20 individuals with frontonasal dysplasia aged 7 to 17 years.
Main Outcome Measures
Prevalence of the several tooth abnormalities and occlusal disorders analyzed.
Results
A total of 19 individuals presented at least one tooth abnormality, with highly variable findings. In radiographs, 20% of individuals (all presenting oral clefts) presented agenesis of lateral incisors and second premolars. No supernumerary teeth were observed; 65% of individuals exhibited occlusal alterations, especially anterior open bite in the two individuals with median cleft lip.
Conclusions
Variable clinical and radiographic alterations were observed, probably due to the large variety of phenotypic characteristics. No specific dental alteration could be related with frontonasal dysplasia.