Hypertensive Cerebral Hemorrhage in a Patient with Turner Syndrome Caused by Deletion in the Short Arm of the X Chromosome

• Published in: Pediatric neurosurgery Vol. 53; no. 3; p. 167
• Main Authors: Hori, Yusuke S, Ohkura, Takahiro, Ebisudani, Yuki, Umakoshi, Michiari, Ishi, Masato, Oda, Kazunori, Aoi, Mizuho, Inoue, Takushi, Furujo, Mahoko, Tanaka, Hiroyuki, Fukuhara, Toru
• Format: Journal Article
• Language: English
• Published: Switzerland 01-01-2018
• Subjects: Adult; Cerebral Hemorrhage; Chromosome Deletion; Chromosomes, Human, X - genetics; Female; Humans; Intracranial Hemorrhage, Hypertensive; Nausea - etiology; Turner Syndrome - complications; Turner Syndrome - genetics; Short-arm deletion; Turner syndrome; Cerebral hemorrhage; X chromosome
• ISSN: 1423-0305
• DOI: 10.1159/000485252

Turner syndrome is a chromosomal disorder usually caused by complete deletion of an X chromosome, with deletion in the short arm of the X chromosome being a rare cause of the condition. Patients with Turner syndrome commonly develop hypertension, and associated vascular complications such as aortic dissection or cerebral hemorrhage have been reported. Cerebral hemorrhage in Turner syndrome is a rare complication, and only a few reports have been published. In these reports, all patients have XO karyotypes or a mosaic type as the cause of Turner syndrome, while no other Turner syndrome types have been documented. In this report, we present for the first time a patient with Turner syndrome caused by deletion in the short arm of the X chromosome who experienced hypertensive hemorrhage as a late complication.