Quantitative Sonographic Differences in Mid-Urethra between Postmenopausal Women with and without Stress Urinary Incontinence

• Published in: Gynecologic and obstetric investigation Vol. 81; no. 3; p. 256
• Main Authors: Olgan, Safak, Mantar, Ozge Piri, Okyay, Recep Emre, Gulekli, Bulent
• Format: Journal Article
• Language: English
• Published: Switzerland 01-01-2016
• Subjects: Aged; Female; Fetal Macrosomia; Humans; Middle Aged; Observer Variation; Parity; Postmenopause; Pregnancy; Reproducibility of Results; Smoking; Ultrasonography - methods; Urethra - diagnostic imaging; Urinary Incontinence, Stress - diagnostic imaging
• ISSN: 1423-002X
• DOI: 10.1159/000445748

The aim of this study was to evaluate midurethral tissue characteristics in continent and stress urinary incontinent postmenopausal women by using transvaginal ultrasound gray-level histogram.
Thirty-seven patients with stress urinary incontinence (SUI) and 77 patients without SUI were evaluated. Vaginal ultrasound gray-level histograms were performed by 2 gynecologists blinded to patients' SUI statuses. The mean gray-level (MGL) of ultrasound gray-level histogram, representing the echogenicity of a region of interest, was measured in the anterior and posterior midurethral wall along a vertical ultrasound beam. The difference in MGL between anterior and posterior (AP difference) midurethra was calculated.
The MGL value of SUI patients was found to be lower in posterior (p = 0.008) and higher in anterior midurethral region (p = 0.001) when compared with control group. In addition, the difference in MGL between anterior and posterior midurethra (AP difference) was found to be higher in SUI group (p < 0.001). Multivariate analysis by logistic regression including confounding factors revealed that AP difference was independently associated with presence of SUI (adjusted OR 1.14, 95% CI 1.08-1.20, p < 0.001). Intra- and inter-observer reproducibility was found to be high with intraclass correlation coefficient of 0.83 and 0.78, respectively.
Postmenopausal SUI patients might have a distinct midurethral echogenicity pattern with the quantitative ultrasonography.