Fast fluorescent blood sugar sensing using phenylboronic acid functionalized N, S-doped carbon dots

• Published in: Carbon Letters Vol. 34; no. 5; pp. 1355 - 1366
• Main Authors: Wang, Xiaoge, Fan, Xiangze, Zhang, Bowen, Zhan, Mengke, Zhu, Jinhua, Hu, Weiping, Liu, Xiuhua
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01-06-2024; 한국탄소학회; Springer Nature B.V
• Subjects: Amino acids; Blood; Carbon; Carbon dots; Characterization and Evaluation of Materials; Chemistry and Materials Science; Chemoreception; Fluorescence; Glucose; Materials Engineering; Materials Science; Morphology; Nanoparticles; Nanotechnology; Original Article; Quantum dots; Raw materials; Room temperature; Temperature; 자연과학일반; Phenylboronic acid; Glucose sensing; Carbon dots
• ISSN: 1976-4251; 2233-4998
• DOI: 10.1007/s42823-024-00696-3

A phenylboric acid functionalized carbon dot (2-FPBA-CD) for rapid fluorescent sensing of glucose in blood was synthesized by simply mixing N, S-doped carbon dots (CDs) with phenylboric acid at room temperature. At pH 7.4, the response of 2-FPBA-CD to glucose could reach equilibrium in a very short time (10 min), with a wide responsive linear range of 19.70 µM to 2.54 mM, which can be applied to the detection of glucose in serum. The mechanism studies showed that the layered carbon film of 2-FPBA-CD aggregated after adding glucose, thereby leading to the fluorescence quenching of 2-FPBA-CD.
Graphical abstract