State-of-the-art-myocardial perfusion stress testing: Static CT perfusion
Large multicenter studies and meta-analysis have documented the diagnostic accuracy and the prognostic implications of stress echocardiography, cardiac magnetic resonance and, mainly, nuclear stress tests. However, none of them provides a comprehensive anatomical and functional evaluation within the...
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| Published in: | Journal of cardiovascular computed tomography Vol. 14; no. 4; pp. 294 - 302 |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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01-07-2020
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| Abstract | Large multicenter studies and meta-analysis have documented the diagnostic accuracy and the prognostic implications of stress echocardiography, cardiac magnetic resonance and, mainly, nuclear stress tests. However, none of them provides a comprehensive anatomical and functional evaluation within the same study as stress CT perfusion. Myocardial CT perfusion is the only non-invasive modality that allows to quantifying coronary stenosis and determining its functional relevance, constituting a potential “one-stop-shop” method for the diagnosis and global management of patients with known or suspected coronary artery disease. In comparison with the dynamic modality, that requires increased radiation, precise acquisition protocols and dedicated post-processing softwares, static CT perfusion was associated with less radiation exposure, non-inferior diagnostic accuracy, easier interpretation of images and is nowadays more widely available. |
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| AbstractList | Large multicenter studies and meta-analysis have documented the diagnostic accuracy and the prognostic implications of stress echocardiography, cardiac magnetic resonance and, mainly, nuclear stress tests. However, none of them provides a comprehensive anatomical and functional evaluation within the same study as stress CT perfusion. Myocardial CT perfusion is the only non-invasive modality that allows to quantifying coronary stenosis and determining its functional relevance, constituting a potential “one-stop-shop” method for the diagnosis and global management of patients with known or suspected coronary artery disease. In comparison with the dynamic modality, that requires increased radiation, precise acquisition protocols and dedicated post-processing softwares, static CT perfusion was associated with less radiation exposure, non-inferior diagnostic accuracy, easier interpretation of images and is nowadays more widely available. |
| Author | Mushtaq, Saima Nicoli, Flavia Andreini, Daniele Pepi, Mauro Annoni, Andrea Bartorelli, Antonio L. Muscogiuri, Giuseppe Formenti, Alberto Mancini, Maria Elisabetta Conte, Edoardo Baggiano, Andrea Tanzilli, Alessandra Guglielmo, Marco Pontone, Gianluca |
| Author_xml | – sequence: 1 givenname: Saima surname: Mushtaq fullname: Mushtaq, Saima organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 2 givenname: Edoardo surname: Conte fullname: Conte, Edoardo organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 3 givenname: Gianluca surname: Pontone fullname: Pontone, Gianluca organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 4 givenname: Andrea surname: Baggiano fullname: Baggiano, Andrea organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 5 givenname: Andrea surname: Annoni fullname: Annoni, Andrea organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 6 givenname: Alberto surname: Formenti fullname: Formenti, Alberto organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 7 givenname: Maria Elisabetta surname: Mancini fullname: Mancini, Maria Elisabetta organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 8 givenname: Marco surname: Guglielmo fullname: Guglielmo, Marco organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 9 givenname: Giuseppe surname: Muscogiuri fullname: Muscogiuri, Giuseppe organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 10 givenname: Alessandra surname: Tanzilli fullname: Tanzilli, Alessandra organization: Sapienza University, Policlinico Umberto I, Rome, Italy – sequence: 11 givenname: Flavia surname: Nicoli fullname: Nicoli, Flavia organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 12 givenname: Antonio L. surname: Bartorelli fullname: Bartorelli, Antonio L. organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 13 givenname: Mauro surname: Pepi fullname: Pepi, Mauro organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy – sequence: 14 givenname: Daniele surname: Andreini fullname: Andreini, Daniele email: daniele.andreini@ccfm.it organization: Centro Cardiologico Monzino, IRCCS, Milan, Italy |
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| Keywords | Functional assessment Static modality CT perfusion Myocardial perfusion |
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