Expression of CGRP mRNAs in the pink salmon, Oncorhynchus gorbuscha

We report the isolation of calcitonin gene-related peptide (CGRP) mRNAs and expression of these RNAs in different tissues in the pink salmon, Oncorhynchus gorbuscha. Hybridization of poly(A+) RNAs indicated a mature CGRP RNA of 1.1 kb. The CGRP-like immunoreactivity occurring in tissues and plasma h...

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Bibliographic Details
Published in:	Peptides (New York, N.Y. : 1980) Vol. 14; no. 5; p. 977
Main Authors:	Maubras, L, Taboulet, J, Pidoux, E, Lasmoles, F, Julienne, A, Milhaud, G, Benson, A A, Moukhtar, M S, Cressent, M
Format:	Journal Article
Language:	English
Published:	United States 01-09-1993
Subjects:	Animals Blotting, Northern Calcitonin Gene-Related Peptide - genetics Female Oncorhynchus - metabolism Organ Specificity - physiology Radioimmunoassay Reproduction - physiology RNA, Messenger - biosynthesis
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Summary:	We report the isolation of calcitonin gene-related peptide (CGRP) mRNAs and expression of these RNAs in different tissues in the pink salmon, Oncorhynchus gorbuscha. Hybridization of poly(A+) RNAs indicated a mature CGRP RNA of 1.1 kb. The CGRP-like immunoreactivity occurring in tissues and plasma had the same relative molecular weight as the synthetic molecule. Variations in CGRP plasma levels were observed during migration, spawning, and postspawning states. These data suggest that CGRP may play an important role during the reproductive cycle of salmon.
ISSN:	0196-9781
DOI:	10.1016/0196-9781(93)90074-Q