Chemical Composition and General Cytotoxicity Evaluation of Essential Oil from the Flowers of Anthemis palestina Reut. ex Boiss., Growing in Jordan

• Published in: Journal of essential oil-bearing plants (Dehra Dun) Vol. 18; no. 5; pp. 1070 - 1077
• Main Authors: Tawaha, Khaled A, Alali, Feras Q, Hudaib, Mohammmad M
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 03-09-2015
• Subjects: 1,8-cineole; acetates; Anthemis; Anthemis palestina (Asteraceae); Artemia; Brine shrimp lethality test (BST); cineole; cytotoxicity; essential oil composition; essential oils; flowers; gas chromatography-mass spectrometry; GC-MS; germacrene D; Jordan; lipid content; oils; somatotropin; spathulenol; thujanol acetate; Jordan
• ISSN: 0976-5026; 0972-060X; 0976-5026
• DOI: 10.1080/0972060X.2014.895190

Chemical composition of the essential oil hydrodistilled from the flowers of Anthemis palestina Reut. ex Boiss. (Asteraceae) collected from Northern Jordan has been analyzed by means of GC and GC-MS. The extracted oil was further evaluated for its general cytotoxicity using Brine Shrimp Lethality test (BST). About 109 compounds, constituting more than 97.0 % of oil content, were successfully identified. Sesquiterpenes (71.4 %), mainly the oxygenated (44.8 %), represented the main oil fraction, while, moderate levels of monoterpenes (19.4 %), mainly as oxygenated (18.5 %), were observed in the studied oil. The principal oil components were spathulenol (9.8 %), germacrene-D (8.9 %), and caryophyllene oxide (6.8 %). Other major identified components were thujanol acetate (3.7 %), E -β-farnesene (3.5 %), bornyl andelate (3.2 %), 1,8-cineole (2.9 %), terpinen-4-ol (2.6 %), salvial-4(14)-en-1-one (2.5 %), and α-cadinol (2.4 %). The Brine shrimp lethality test (BST) results showed a potent general cytotoxicity with LC of 12.0 mg/mL.