The use of α-(aryl)-4-morpholineacetonitriles (masked acyl anion equivalents) in 1,4-additions to α,β-unsaturated esters and nitriles. A versatile synthetic route to 6-aryl-3(2H) pyridazinones

The use of α-(aryl)-4-morpholineacetonitriles (masked acyl anion equivalents) in 1,4-additions to α,β-unsaturated esters and nitriles. A versatile synthetic route to 6-aryl-3(2H) pyridazinones

The use of α‐(substituted‐phenyl)‐4‐morpholineacetonitriles in 1,4‐additions to ethyl acrylate, ethyl crotonate, methyl α‐methylacrylate, acrylonitrile, methylacrylonitrile, crotononitrile and cinnamonitrile was studied. A convenient route to 6‐aryl‐4,5‐dihydro‐3(2H) pyridazinones from aryl aldehyde...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry Vol. 15; no. 6; pp. 881 - 892
Main Authors: Albright, J. D., Mcevoy, F. J., Moran, Daniel B.
Format: Journal Article
Language:English
Published: Hoboken Wiley-Blackwell 01-09-1978
Wiley‐Blackwell
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Summary:The use of α‐(substituted‐phenyl)‐4‐morpholineacetonitriles in 1,4‐additions to ethyl acrylate, ethyl crotonate, methyl α‐methylacrylate, acrylonitrile, methylacrylonitrile, crotononitrile and cinnamonitrile was studied. A convenient route to 6‐aryl‐4,5‐dihydro‐3(2H) pyridazinones from aryl aldehydes and heterocyclic aldehydes was developed.
Bibliography:istex:584310FB0C23A8054F174C18187B3ADF709C29DB
ArticleID:JHET5570150601
ark:/67375/WNG-Z9HRS9NS-B
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570150601