Regio and stereoselective catalytic five-component cascades of diverse heterocyclic bisallenes: tri-directional exploration of biochemical space

We report protecting group free Pd(0) catalyzed cascade syntheses of molecular scaffolds built from heterocyclic bisallenes. These generate novel molecular architecture permitting tri-directional exploration of biochemical space. [Display omitted]

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Bibliographic Details
Published in:	Tetrahedron Vol. 70; no. 1; pp. 110 - 122
Main Authors:	Elboray, Elghareeb E., Aly, Moustafa F., Abbas-Temirek, Hussien H., Churchill, Gwydion H., Grigg, Ronald
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 07-01-2014
Subjects:	Architecture Biochemical space Biochemistry Cascades Catalysis Catalysts Exploration Multiple heterocycles Palladium Peptides Scaffolds Stereoselective Tetrahedrons Multiple heterocycles Palladium Peptides Biochemical space Stereoselective
Online Access:	Get full text
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Description
Summary:	We report protecting group free Pd(0) catalyzed cascade syntheses of molecular scaffolds built from heterocyclic bisallenes. These generate novel molecular architecture permitting tri-directional exploration of biochemical space. [Display omitted]
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0040-4020 1464-5416
DOI:	10.1016/j.tet.2013.10.060