Iron (III)‐porphyrin Complex FeTSPP as an efficient catalyst for synthesis of tetrazole derivatives via [2 + 3]cycloaddition reaction in aqueous medium

• Published in: Applied organometallic chemistry Vol. 33; no. 8
• Main Authors: El‐Remaily, Mahmoud Abd El Aleem Ali Ali, Elhady, O.M.
• Format: Journal Article
• Language: English
• Published: Chichester Wiley Subscription Services, Inc 01-08-2019
• Subjects: aqueous medium; Aqueous solutions; Catalysis; Catalysts; Chemical synthesis; Chemistry; Coordination compounds; Cycloaddition; Derivatives; environmentally benign protocol; guanidinyltetrazole; Iron; metal complex FeTSPP; Nitriles; Organic chemistry; Tetrazoles; “click” chemistry
• ISSN: 0268-2605; 1099-0739
• DOI: 10.1002/aoc.4989

The metal complex (5,10,15,20‐tetrakis‐(4‐sulfonatophenyl)‐porphyrin‐iron (III) chloride (FeTSPP) was new employed in an environmentally benign protocol as an efficient catalyst for a “click” chemistry approach for the synthesis of tetrazole and guanindinyltetrazole derivatives via [2 + 3] cycloaddition reaction of nitriles and azide derivatives in aqueous medium. The synthesized compounds were obtained in excellent yield, short reaction times and a recoverable catalyst.
The metal complex (5,10,15,20‐tetrakis‐(4‐sulfonatophenyl)‐porphyrin‐iron (III) chloride (FeTSPP) was new employed in an environmentally benign protocol as an efficient catalyst for a “click” chemistry approach for the synthesis of tetrazole and guanindinyltetrazole derivatives via [2 + 3] cycloaddition reaction of nitriles and azide derivatives in aqueous medium. The synthesized compounds were obtained in excellent yield, short reaction times and a recoverable catalyst.