Hydrodehalogenation of Haloarenes by a Sodium Hydride–Iodide Composite

Hydrodehalogenation of Haloarenes by a Sodium Hydride–Iodide Composite

A simple protocol for hydrodebromination and ‐deiodination of halo(hetero)arenes was enabled by sodium hydride (NaH) in the presence of lithium iodide (LiI). Mechanistic studies showed that an unusual concerted nucleophilic aromatic substitution operates in the present process. Ein einfaches Protoko...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie Vol. 129; no. 7; pp. 1866 - 1870
Main Authors: Ong, Derek Yiren, Tejo, Ciputra, Xu, Kai, Hirao, Hajime, Chiba, Shunsuke
Format: Journal Article
Language:English
Published: Weinheim Wiley Subscription Services, Inc 06-02-2017
Subjects:
Aromatic compounds
Chemistry
DFT-Rechnungen
Halogenarene
Hydrodehalogenierung
Iodides
Lithium
Natriumhydrid
Reduktionen
Sodium
Sodium hydrides
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A simple protocol for hydrodebromination and ‐deiodination of halo(hetero)arenes was enabled by sodium hydride (NaH) in the presence of lithium iodide (LiI). Mechanistic studies showed that an unusual concerted nucleophilic aromatic substitution operates in the present process. Ein einfaches Protokoll für die Hydrodebromierung und ‐deiodierung von Halogen(hetero)arenen wurde entwickelt, das Natriumhydrid (NaH) in Gegenwart von Lithiumiodid (LiI) verwendet. Mechanistische Studien zeigen, dass eine ungewöhnliche konzertierte nukleophile aromatische Substitution stattfindet.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0044-8249
1521-3757
DOI:10.1002/ange.201611495