Sensorineural Deafness Following Tacrolimus Use

Sensorineural Deafness Following Tacrolimus Use

Early trials of tacrolimus in renal transplant recipients have not revealed hearing loss as an adverse effect. Here, we present a case report and a review of the literature of deafness after tacrolimus use. The review of the literature and our experience suggested that the possible reason for hearin...

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Bibliographic Details
Published in:Experimental and clinical transplantation Vol. 18; no. 1; pp. 110 - 111
Main Authors: Lakshmi, Boju Sangeetha, Vidya, Bhukya, Hari Krishna Reddy, Mogili, Venkata Kumar, Anil Cheni, Ram, Rapur, Siva Kumar, Vishnubotla
Format: Journal Article
Language:English
Published: Başkent Üniversitesi 01-02-2020
Subjects:
Tıp
Ankara
Türkiye
Drug effects
Renal transplant
Hearing loss
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Summary:Early trials of tacrolimus in renal transplant recipients have not revealed hearing loss as an adverse effect. Here, we present a case report and a review of the literature of deafness after tacrolimus use. The review of the literature and our experience suggested that the possible reason for hearing loss could be due to an initiation of a sudden spike in the tacrolimus serum level, which was later worsened by its cumulative toxic effect.
ISSN:1304-0855
2146-8427
DOI:10.6002/ect.2017.0114