A MEGA RNA-editing tool

In this Tools of the Trade article, Victor Tieu describes the development of MEGA, a platform that exploits the RNA-targeting capability of CRISPR–Cas13d and demonstrates its use to improve the anti-tumour activity of CAR T cells.

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Bibliographic Details
Published in:	Nature reviews. Cancer Vol. 24; no. 8; p. 519
Main Author:	Tieu, Victor
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01-08-2024 Nature Publishing Group
Subjects:	631/1647/1511 631/67/1059/2325 Biomedical and Life Sciences Biomedicine Cancer Research CRISPR CRISPR-Cas Systems Humans Lymphocytes T Neoplasms - genetics RNA Editing Tools of the Trade
Online Access:	Get full text
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Description
Summary:	In this Tools of the Trade article, Victor Tieu describes the development of MEGA, a platform that exploits the RNA-targeting capability of CRISPR–Cas13d and demonstrates its use to improve the anti-tumour activity of CAR T cells.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1474-175X 1474-1768 1474-1768
DOI:	10.1038/s41568-024-00695-6