Study of the correlation between clinical efficiency of impaza and serum ADMA level

Correlation between superlow-dose antibodies to endothelial NO synthase (Impaza) and serum level of ADMA was evaluated in a double blind placebo-controlled study. The reduction of ADMA in patients with erectile dysfunction after impaza treatment was paralleled by improvement of clinical symptoms. No...

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Bibliographic Details
Published in:	Bulletin of experimental biology and medicine Vol. 145; no. 3; pp. 367 - 370
Main Authors:	Zhavbert, E. S., Tarasov, S. A., Dugina, J. L., Sergeeva, S. A., Gamidov, S. I., Mazo, E. B., Epstein, O. I.
Format:	Journal Article
Language:	English
Published:	Boston Springer US 01-03-2008 Springer Nature B.V
Subjects:	Adult Antibodies - therapeutic use Arginine - analogs & derivatives Arginine - blood Biomedical and Life Sciences Biomedicine Cell Biology Double-Blind Method Erectile Dysfunction - drug therapy Experimental Methods for Clinical Practice Humans Internal Medicine Laboratory Medicine Male Nitric Oxide Synthase Type III - immunology Pathology superlow-dose antibodies to endothelial NO synthase ADMA erectile dysfunction
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Summary:	Correlation between superlow-dose antibodies to endothelial NO synthase (Impaza) and serum level of ADMA was evaluated in a double blind placebo-controlled study. The reduction of ADMA in patients with erectile dysfunction after impaza treatment was paralleled by improvement of clinical symptoms. No clear-cut correlation between ADMA level and impaza effect was detected.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-008-0093-7