Stimulated Low-Frequency Raman Scattering in Albumin

• Published in: Journal of Russian laser research Vol. 40; no. 1; pp. 71 - 75
• Main Authors: Shevchenko, M. A., Chaikov, L. L., Kirichenko, M. N., Kudryavtseva, A. D., Mironova, T. V., Savichev, V. I., Sokovishin, V. V., Tcherniega, N. V., Zemskov, K. I.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-01-2019; Springer Nature B.V
• Subjects: Elastic properties; Elastic scattering; Interferometers; Lasers; Microwaves; Nanoparticles; Optical Devices; Optics; Photonics; Physics; Physics and Astronomy; Raman spectra; Resonant frequencies; RF and Optical Engineering; Serum albumin; stimulated scattering; nonlinear optics; nanoparticles; laser; biharmonic pump; spectrum; human serum albumin; bovine serum albumin
• ISSN: 1071-2836; 1573-8760
• DOI: 10.1007/s10946-019-09771-x

Stimulated low-frequency Raman scattering (SLFRS) can provide important information on elastic properties of different nanoparticle systems, in particular, biological nanostructures. In the present study, for the first time we investigate low-frequency vibrational modes in human and bovine serum albumin (HSA and BSA), in view of the SLFRS method. We use 20 ns ruby-laser pulses for excitation. The SLFRS frequency shifts, corresponding to acoustic eigenfrequencies of the sample, are registered by Fabry–Pérot interferometers. For HAS, the set of eigenfrequencies obtained is 6 GHz (0.2 cm
−
1
), 10 GHz (0.33 cm
−
1
), and 15.6 GHz (0.52 cm
−
1
), while for BSA, it is 8.7 GHz (0.29 cm
−
1
) and 16.5 GHz (0.55 cm
−
1
). We also measure the conversion efficiency and threshold. The SLFRS can be applied for biological-object identification and impact on the biological objects.