Intensive insulin therapy for acute hyperglycemia

There is growing evidence that control of hyperglycemia in the critically ill patient improves outcome. Normalizing blood glucose levels decreases the risk of developing sepsis, end-organ damage, and hospital mortality. Critical care clinicians must be familiar with current and benchmark research su...

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Bibliographic Details
Published in:	AACN advanced critical care Vol. 18; no. 2; p. 200
Main Authors:	Read, Julia Lindeman, Cheng, Eugene Y
Format:	Journal Article
Language:	English
Published:	United States 01-04-2007
Subjects:	Acute Disease Benchmarking - organization & administration Causality Clinical Protocols Cost of Illness Critical Care - methods Critical Illness Drug Monitoring Evidence-Based Medicine Humans Hyperglycemia - complications Hyperglycemia - drug therapy Hypoglycemic Agents - therapeutic use Insulin - therapeutic use Medical Records Outcome and Process Assessment (Health Care) Personnel, Hospital - education Program Development Program Evaluation
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Summary:	There is growing evidence that control of hyperglycemia in the critically ill patient improves outcome. Normalizing blood glucose levels decreases the risk of developing sepsis, end-organ damage, and hospital mortality. Critical care clinicians must be familiar with current and benchmark research supporting control of hyperglycemia and use this knowledge to ensure appropriate application of evidence-based practice for decreasing or preventing complications in the critically ill patient. This article describes the effects of hyperglycemia and discusses the evidence supporting tight glycemic control in such patients. The necessary steps to implement an intensive insulin therapy protocol for control of acute hyperglycemia are detailed.
ISSN:	1559-7768
DOI:	10.1097/01.AACN.0000269264.22041.1c