Exploring catalytic efficacy and anti-bacterial performance with molecular docking analysis of g-C3N4-grafted-Ag doped SnO2 QDs

• Published in: Research on chemical intermediates Vol. 50; no. 4; pp. 1661 - 1678
• Main Authors: Ameen, Muhammad Tayyab, Haider, Ali, Shahzadi, Iram, Shahbaz, Atif, Ul-Hamid, Anwar, Ullah, Hameed, Khan, Sherdil, Ikram, Muhammad
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01-04-2024; Springer Nature B.V
• Subjects: Carbon nitride; Catalysis; Chemistry; Chemistry and Materials Science; Effectiveness; Inorganic Chemistry; Molecular docking; Physical Chemistry; Quantum dots; Silver; Tin dioxide; Tin oxides; Silver; Quantum dots; Graphitic carbon nitride
• ISSN: 0922-6168; 1568-5675
• DOI: 10.1007/s11164-024-05241-5

The current work demonstrates the controlled synthesis of graphitic carbon nitride grafted silver (g-C
3
N
4
-g-Ag) doped tin oxide (SnO
2
) quantum dots (QDs) using the co-precipitation method. This research aimed to decrease the charge recombination rate of SnO
2
and enhance their multifunctional effectiveness as catalysts and antibacterial agents with molecular docking analysis. The doping of g-C
3
N
4
-g-Ag increased the charge separation efficacy and number of active sites, resulting in the enhancement of catalytic and antibacterial activities. 6 mL of g-C
3
N
4
-g-Ag doped SnO
2
QDs indicated remarkable dye removal activity of over 97.7%, which signifies its potential application in various environmental settings. Furthermore, the doped QDs demonstrated the 4.05 ± 0.08 mm inhibition area contrary to multiple drug resistant (MDR)
Staphylococcus aureus
(
S. aureus
). The inhibitory effect of g-C
3
N
4
-g-Ag doped SnO
2
QDs on DNA gyrase
S. aureus
and tyrosyl-tRNA synthetase
S. aureus
was elucidated using molecular docking analysis, supporting their bactericidal activity.