First used of Alkylbenzimidazole-Cobalt(II) complexes as a catalyst for the N-Alkylation of amines with alcohols under solvent-free medium

• Published in: Journal of organometallic chemistry Vol. 918; p. 121285
• Main Authors: Şahin, Neslihan, Yıldırım, İlkay, Özdemir, Namık, Gürbüz, Nevin, Özdemir, İsmail
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-07-2020
• Subjects: Cobalt; Crystal structure; N-alkylation; N-alkylbenzimidazole; Solvent-free; N-alkylbenzimidazole; Cobalt; Solvent-free; N-alkylation; Crystal structure
• ISSN: 0022-328X; 1872-8561
• DOI: 10.1016/j.jorganchem.2020.121285

In this study, alkylbenzimidazole-cobalt(II)-catalyzed direct N-alkylation reactions of amines with alcohols derivatives have been investigated under solvent-free medium. For this purpose, a series of cobalt(II) complexes bearing N-alkylbenzimidazole complexes have been synthesized and novel complexes fully characterized by elemental analysis, FT-IR, 1H NMR and, 13C{1H} NMR spectroscopies. Also, the structure of the complex 2a has been confirmed by X-ray crystallography. Generally, the N-alkylating reaction is usually performed in toluene with various metal complexes including cobalt. In this catalytic study of complexes, 2a-c has carried out in without solvent and alcohol acted both as solvent and reactant. Conversion and selectivity of amine products according to imine products for alkylation reactions have been seen high yield in medium solvent-free relative to in toluene.
[Display omitted]
•Alkylbenzimidazole-Co(II) complexes were synthesized and characterized.•These complexes were used the first time for direct N-alkylation reactions of amine.•Alkylation reactions were performed under solvent-free conditions.•This reaction was found to be more efficient and selective than other Co complexes.