Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case

Abstract Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric...

Full description

Saved in:

Bibliographic Details
Published in:	The mental health clinician Vol. 12; no. 3; pp. 214 - 218
Main Authors:	Ayub, Shahana, Saboor, Sundas, Usmani, Sadia, Javed, Sana, Tonpouwo, Gauvain Kankeu, Ahmed, Saeed
Format:	Journal Article
Language:	English
Published:	College of Psychiatric & Neurologic Pharmacists 01-06-2022 American Association of Psychiatric Pharmacists
Subjects:	bariatric surgery bipolar disorder Case Reports lithium toxicity malabsorption obesity
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Abstract Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms after undergoing Roux-en-Y gastric bypass. The mechanism of lithium toxicity is discussed; recommendations for clinicians regarding lithium use in postsurgical patients are provided; and previous case reports of lithium toxicity post-gastric bypass surgery are analyzed. Awareness and education of lithium absorption changes postbariatric surgery is essential for optimal patient care. Close clinical and drug concentration level monitoring is warranted.
ISSN:	2168-9709 2168-9709
DOI:	10.9740/mhc.2022.06.214