Porcine bladder extracellular matrix for closure of a large defect in a burn contracture release

Porcine bladder extracellular matrix for closure of a large defect in a burn contracture release

Porcine bladder extracellular matrix (PBEM) is an innovative wound healing alternative to traditional wound closure and reconstruction. By stimulating blood vessel formation and chemotaxis of progenitor cells to the site of injury, it promotes a unique healing environment favouring regeneration of n...

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Bibliographic Details
Published in:Journal of wound care Vol. 21; no. 9; pp. 454 - 456
Main Authors: Mitchell, K.B., Gallagher, J.J.
Format: Journal Article
Language:English
Published: London MA Healthcare 01-09-2012
Subjects:
Animals
Burns - surgery
Contracture - surgery
Extracellular Matrix - transplantation
Humans
Male
Middle Aged
Neck Injuries - surgery
Practice
Swine
Urinary Bladder - cytology
Wound Healing - physiology
acellular dermal matrix
chronic wound
burn wound reconstruction
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Summary:Porcine bladder extracellular matrix (PBEM) is an innovative wound healing alternative to traditional wound closure and reconstruction. By stimulating blood vessel formation and chemotaxis of progenitor cells to the site of injury, it promotes a unique healing environment favouring regeneration of native tissue over scar formation. This is the first clinical report describing the novel use of PBEM scaffold material to close a large defect resulting from a burn contracture release. The benefits of this method are the improved functional and cosmetic result. PBEM-moderated tissue regeneration may serve a valuable role in burn reconstruction.
ISSN:0969-0700
2052-2916
DOI:10.12968/jowc.2012.21.9.454