More on human immunodeficiency virus embryopathy

• Published in: Pediatrics (Evanston) Vol. 80; no. 4; pp. 512 - 516
• Main Authors: IOSUB, S, BAMJI, M, STONE, R. K, GROMISCH, D. S, WASSERMAN, E
• Format: Journal Article
• Language: English
• Published: Elk Grove Village, IL American Academy of Pediatrics 01-10-1987
• Subjects: Acquired Immunodeficiency Syndrome - congenital; Acquired Immunodeficiency Syndrome - pathology; AIDS-Related Complex - congenital; AIDS/HIV; Biological and medical sciences; Face - abnormalities; Female; Fetal Growth Retardation - etiology; Growth Disorders - embryology; Head - abnormalities; Human viral diseases; Humans; Infant; Infectious diseases; Male; Medical sciences; Microcephaly - embryology; Nose - abnormalities; Pregnancy; Skull - abnormalities; Viral diseases; Human; Infection; Virus; Fetal diseases; Pregnancy disorders; Malformation; Viral disease; Retroviridae; Development; Infant; Human immunodeficiency virus
• ISSN: 0031-4005; 1098-4275
• DOI: 10.1542/peds.80.4.512

Eight patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex, ranging in age from 4 to 33 months, were evaluated for the presence of dysmorphic features recently described as human immunodeficiency virus embryopathy. Birth data and growth charts were available. Growth failure, a prominent box-like head, large wide eyes, and a well-formed philtrum were seen in the majority of patients. The significance of hypertelorism, obliquity of eyes, long palpebral fissures, blue scleras, depressed bridge of nose, and prominent upper vermilion border is discussed.