Photochemical Synthesis of 1,4‐Dicarbonyl Containing Quinoxalin‐2(1H)‐Ones through Consecutive Photoredox Catalysis

Photochemical Synthesis of 1,4‐Dicarbonyl Containing Quinoxalin‐2(1H)‐Ones through Consecutive Photoredox Catalysis

Herein, we report a photochemical synthesis of 1,4‐dicarbonyl containing quinoxalin‐2(1H)‐ones through consecutive photoredox catalysed reactions. A wide range of C3‐modified quinoxalin‐2(1H)‐ones were obtained in 53–91% yields by this approach. Mechanistic studies including radical trapping, EPR st...

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Bibliographic Details
Published in:Advanced synthesis & catalysis Vol. 366; no. 8; pp. 1833 - 1839
Main Authors: Xu, Cong‐Lun, Bao, Ye‐Peng, Xie, Yang, Ye, Hai‐Bing, Xuan, Jun
Format: Journal Article
Language:English
Published: Heidelberg Wiley Subscription Services, Inc 23-04-2024
Subjects:
Consecutive photoredox catalysis
Diazoalkanes
Heterocycles
Photoredox catalysis
Synthesis
Synthetic methods
Visible light
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Summary:Herein, we report a photochemical synthesis of 1,4‐dicarbonyl containing quinoxalin‐2(1H)‐ones through consecutive photoredox catalysed reactions. A wide range of C3‐modified quinoxalin‐2(1H)‐ones were obtained in 53–91% yields by this approach. Mechanistic studies including radical trapping, EPR studies, D‐labelling investigations, and many other control experiments well explained the proposed consecutive photoredox mechanism.
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.202301393