Effect of the Chemical Structure of Chitosan Copolymers with Oligolactides on the Morphology and Properties of Macroporous Hydrogels Based on Them

• Published in: Polymer science. Series B Vol. 63; no. 5; pp. 536 - 543
• Main Authors: Popyrina, T. N., Svidchenko, E. A., Demina, T. S., Akopova, T. A., Zelenetsky, A. N.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01-09-2021; Springer Nature B.V
• Subjects: Chemistry; Chemistry and Materials Science; Chitosan; Crosslinking; Extrusion; Graft copolymers; Heat treatment; Hydrogels; Moisture absorption; Molecular structure; Morphology; Natural Polymers; Oligomers; Polymer Sciences
• ISSN: 1560-0904; 1555-6123
• DOI: 10.1134/S1560090421050109

Materials in the form of thermally crosslinked films and macroporous hydrogels based on graft copolymers of chitosan with lactide oligomers of various stereochemical compositions synthesized by solid-state reactive extrusion are obtained and studied. It is shown that the chemical structure of the copolymers and the molecular weight of the initial chitosan significantly affect the morphology and properties of the materials. The heterogeneous morphology of materials based on the semicrystalline lactide oligomer leads to a decrease in the efficiency of crosslinking of the materials during heat treatment and a higher degree of moisture absorption of macroporous hydrogels.