Does Biological Longevity Depend on the Magnetic Fields?

• Published in: Russian journal of physical chemistry. B Vol. 17; no. 1; pp. 128 - 134
• Main Author: Buchachenko, A. L.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01-02-2023; Springer Nature B.V
• Subjects: Chemical Physics of Biological Processes; Chemistry; Chemistry and Materials Science; Deoxyribonucleic acid; DNA; Electron transfer; Isotope effect; Magnetic fields; Nuclei (cytology); Physical Chemistry; Synthesis; isotope effects; DNA synthesis; longevity; genes; magnetic effects
• ISSN: 1990-7931; 1990-7923
• DOI: 10.1134/S1990793123010037

Discovery of magnetic isotope effect in chemistry elucidated new frontiers in magneto-chemistry of genes. The loading of polymerases with
25
Mg
2+
,
43
Ca
2+
, and
67
Zn
2+
ions carrying magnetic nuclei instead of
24
Mg
2+
,
40
Ca
2+
, and
64
Zn
2+
ions with nonmagnetic nuclei disclosed a huge isotope effect: nuclear magnetic ions decrease the rate of the DNA and gene synthesis by 3–5 times with respect to ions with nonmagnetic nuclei. The effect certifies new, enzymatic radical pair mechanism, which includes electron transfer from the growing DNA chain to the catalyzing ion as a first step of the mechanism. The key processes of gene functioning—DNA synthesis, DNA damage, and DNA repair – are shown to be magnetically controlled and mechanism of the control is physically substantiated. The effect of magnetic fields on the DNA synthesis, Hayflick limit, and biological longevity is discussed.