Preparation and Characterization of Carboxyl Functionalized Fluorescent Mesoporous Silica Nanoparticles Containing 8-Hydroxyquinolinate Zinc Complexes

• Published in: Journal of Wuhan University of Technology. Materials science edition Vol. 34; no. 4; pp. 973 - 978
• Main Authors: Wang, Wanxia, Wang, Youyun, Wang, Yu, Zhu, Hongda, Sun, Honghao, Liu, Mingxing
• Format: Journal Article
• Language: English
• Published: Wuhan Wuhan University of Technology 01-08-2019; Springer Nature B.V
• Subjects: Biomaterials; Carboxyl group; Chemistry and Materials Science; Drug delivery systems; Field emission microscopy; Fluorescence; Fourier transforms; Infrared spectrometers; Infrared spectroscopy; Materials Science; Microscopy; Nanoparticles; Photon correlation spectroscopy; Scanning electron microscopy; Silicon dioxide; Zinc; synthesis; mesoporous silica nanoparticles; carboxyl functionalization; 8-hydroxyquinolinate zinc complexes; fluorescent
• ISSN: 1000-2413; 1993-0437
• DOI: 10.1007/s11595-019-2146-3

Fluorescent mesoporous silica nanoparticles functionalized with carboxyl group (Znq-CMS-COOH) were successfully synthesized by in situ formation route of 8-hydroxyquinolinate zinc complexes in channels of mesoporous silica nanoparticles and post-grafting of carboxyl group on the surface. Moreover, the particle size and structural properties of Znq-CMS-COOH were characterized by transmission electron microscopy (TEM), field emission scanning electron microscopy (FE-SEM), dynamic light scattering (DLS). Fourier transform infrared spectroscopy (FT-IR), UV-vis spectrometer, fluorescence spectrometer and nitrogen adsorption-desorption measurements. The obtained results suggest that the Znq-CMS-COOH presents the uniform spherical shape with the mean diameter of about 85 nm and the obvious wormhole arrangement mesoporous. In addition, the Znq-CMS-COOH possesses green fluorescence with the emission peaks at 495 nm. So the Znq-CMS-COOH, which is beneficial to further modification and tracing, might be a great potential carrier for applying in drug delivery system in the future.