Amyotrophic Lateral Sclerosis

Progress has been made in understanding the genetic defects and the pathophysiology of this crippling motor neuron disease (commonly called Lou Gehrig’s disease). However, this information has not yet led to a successful intervention that alters the course of the disease.

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 377; no. 2; pp. 162 - 172
Main Authors:	Brown, Robert H, Al-Chalabi, Ammar
Format:	Journal Article
Language:	English
Published:	United States Massachusetts Medical Society 13-07-2017
Subjects:	Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - epidemiology Amyotrophic Lateral Sclerosis - genetics Amyotrophic Lateral Sclerosis - physiopathology Amyotrophic Lateral Sclerosis - therapy Genes Genetic Variation Humans Motor neuron diseases Motor task performance Mutation Neurons Pathology Survival Analysis
Online Access:	Get full text
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Description
Summary:	Progress has been made in understanding the genetic defects and the pathophysiology of this crippling motor neuron disease (commonly called Lou Gehrig’s disease). However, this information has not yet led to a successful intervention that alters the course of the disease.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMra1603471