Lipoatrophic panniculitis in an adolescent

• Published in: Pediatric dermatology Vol. 37; no. 3; pp. 572 - 573
• Main Authors: Comstock, Jeanette R., Buhalog, Brittany, Peebles, J. Klint, Hinshaw, Molly A., Co, Dominic O., Arkin, Lisa M.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01-05-2020
• Subjects: Adolescent; Atrophy; Biopsy; Case reports; Child; Children; Connective Tissue Diseases; dermatopathology; Fasciitis; Genotype & phenotype; Humans; Inflammation; Leukocytes (eosinophilic); lipodystrophy; Medical diagnosis; panniculitis; Panniculitis - diagnosis; Pediatrics; Plaques; Skin diseases; subcutaneous tissue; Teenagers; therapy—systemic; dermatopathology; subcutaneous tissue; panniculitis; therapy-systemic; lipodystrophy
• ISSN: 0736-8046; 1525-1470
• DOI: 10.1111/pde.14127

Lipoatrophic panniculitis (LP) is a rare childhood panniculitis characterized by sclerotic, atrophic plaques on the extremities. We present a case of LP diagnosed during the inflammatory phase that was difficult to distinguish clinically from eosinophilic fasciitis. This report adds to the limited phenotypic spectrum of LP by differentiating the clinical features of disease activity from disease damage and highlighting the importance of biopsy in establishing a diagnosis.