Ulectomy in a patient with nephrotic syndrome under investigation for Galloway‐Mowat syndrome: a case report

• Published in: Special care in dentistry Vol. 44; no. 4; pp. 1054 - 1058
• Main Authors: Alves, Gabriela Reis, Javaroni, Julia Biliato, Moura, Ana Paula Gomes e, Consolaro, Alberto, Segato, Raquel Assed Bezerra
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01-07-2024
• Subjects: Case reports; Childrens health; Gum disease; Histopathology; Immunosuppressive agents; immunosuppressive medications; Incisors; Kidney diseases; Kidney transplantation; Kidney transplants; Medical diagnosis; Mutation; Nephrotic syndrome; NUP107; Oral cavity; oral manifestations; Palate; Patients; Quality of life; Surgery; Surgical outcomes; Surgical techniques; ulectomy; ulectomy; NUP107; immunosuppressive medications; nephrotic syndrome; oral manifestations
• ISSN: 0275-1879; 1754-4505; 1754-4505
• DOI: 10.1111/scd.12971

The aim of this study is to report a case in which a patient with nephrotic syndrome underwent surgery to remove fibrous gum tissue (ulectomy). An 8‐year‐old patient, diagnosed with early onset nephrotic syndrome due to a mutation in the NUP107 gene, had received a kidney transplant and was therefore taking various medications, including immunosuppressants. On oral examination, the patient was found to have a fibrous gingiva that was preventing the eruption of the upper permanent central incisors. A ulectomy was performed and the gingival tissue was sent for histopathological analysis, which showed normal aspects. The upper right central incisor was seen in the oral cavity 15 days after surgery. A second procedure was carried out to facilitate the eruption of the upper left incisor, which was visualized in the oral cavity 30 days later. In addition, oral manifestations such as maxillary atresia, ogival palate and mouth breathing were observed. Therefore, the role of the dental surgeon in the lives of transplanted children is considered important, as they often take various medications that can affect their oral health. Thus, early diagnosis and effective treatment will be essential to prevent future malocclusions and thus improve the quality of life of these patients.