Photo-active hybrid materials based on polyoxometalate anion and ethidium cation

• Published in: Journal of molecular structure Vol. 1301; p. 137170
• Main Authors: Mishra, Neeraj Kumar, Supriya, Sabbani
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 05-04-2024
• Subjects: DNA binding study; Eithidium cation; Ion-pair compounds; Polyoxometalates; DNA binding study; Polyoxometalates; Eithidium cation; Ion-pair compounds
• ISSN: 0022-2860; 1872-8014
• DOI: 10.1016/j.molstruc.2023.137170

•The polyoxometalate compounds, stabilized by the biologically relevant ethidium counter cations.•The binding studies of Keggin-Ethidium hybrid with CT-DNA (calf thymus DNA).•The single crystal X-ray structure of Keggin-Ethidium hybrid compounds.•The supramolecular interactions between Keggin polyanion and ethidium cation.
We report the synthesis and photoluminescence (PL) properties of three compounds [C21H20N3]2[HPMo12O40] (1), [C21H20N3]3[PW12O40]∙4C3H7NO (2) and [C21H20N3]4[SiW12O40] (3) consisting of ethidium cation (3,8-diamino-5-ethyl-6-phenylphenanthridinium) and Keggin type polyoxometalates. Compounds 1, 2 and 3 have been characterized unambiguously by the single crystal X-ray diffraction studies. The binding studies of inorganic-organic hybrid compounds 1, 2 and 3 with CT-DNA (calf thymus DNA) have been carried out and monitored by UV–Vis- and emission-spectroscopy. The compounds 1 and 2 show fluorescence enhancement where as compound 3 with silicotungstate polyanion shows fluorescence quenching. The photoluminescence properties of three hybrid compounds arise due to the interaction of ethidium cation with DNA. We have demonstrated that the interaction between ethidium cation and CT-DNA is influenced by a particular type of polyoxometalate (POM) Keggin anion. The crystal structures show supramolecular interactions between the Keggin anion and ethidium cation. Compounds 1, 2 and 3 are further characterized by routine spectral analysis.
[Display omitted]