Production of pyrogenic exotoxins in group A streptococci isolated from patients in Zagreb, Croatia

• Published in: European journal of clinical microbiology & infectious diseases Vol. 11; no. 6; pp. 540 - 543
• Main Authors: BEGOVAC, J, GMAJNICKI, B, SCHLIEVERT, P. M, JOHNSON, D. R, KAPLAN, E. L
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01-06-1992
• Subjects: Adult; Aged; Bacterial Proteins; Bacteriology; Biological and medical sciences; Child; Child, Preschool; Exotoxins - biosynthesis; Female; Fundamental and applied biological sciences. Psychology; Humans; Male; Membrane Proteins; Microbiology; Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains; Pyrogens - biosynthesis; Streptococcus pyogenes - metabolism; Yugoslavia; Yugoslavia; Streptococcaceae; Toxin; Microbiology; Streptococcus A; Micrococcales; Bacteria; Biosynthesis; Exotoxin; Bacteriological investigation; In vitro; Pyrogen; Strain
• ISSN: 0934-9723; 1435-4373
• DOI: 10.1007/BF01960810

The pyrogenic exotoxin profiles were determined of group A streptococci isolated from patients in Zagreb, Croatia in the period 1989-1990. A total of 12 strains were studied, five from patients with serious infections and seven from patients with uncomplicated infections. Serotypes M1 and M3 were found in seven (58%) patients. Seven strains produced exotoxin A and ten strains exotoxin B. The proportion of exotoxin A and B producing strains in patients with severe infections (3 patients respectively) was similar to that found in patients with uncomplicated infections (4 and 7 patients respectively).