Posttransplant diabetes and hypertension: Pathophysiologic insights and therapeutic rationale

New-onset diabetes after transplantation and hypertension are very common after renal transplantation and are associated with adverse graft and cardiovascular outcomes. A thorough understanding of the unique factors that operate in renal transplant recipients is essential for the proper evaluation a...

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Bibliographic Details
Published in:	Current diabetes reports Vol. 8; no. 3; pp. 221 - 227
Main Authors:	Salifu, Moro O., Tedla, Fasika, Aytug, Serhat, Hayat, Amir, McFarlane, Samy I.
Format:	Journal Article
Language:	English
Published:	New York Current Science Inc 01-06-2008
Subjects:	Diabetes Diabetes Mellitus - etiology Diabetes Mellitus - pathology Diabetes Mellitus - therapy Humans Hypertension - complications Hypertension - etiology Hypertension - pathology Hypertension - therapy Kidney Transplantation - adverse effects Medicine Medicine & Public Health Oral Glucose Tolerance Test Renal Transplant Recipient Nephrol Dial Transplant Acute Rejection Tacrolimus
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Summary:	New-onset diabetes after transplantation and hypertension are very common after renal transplantation and are associated with adverse graft and cardiovascular outcomes. A thorough understanding of the unique factors that operate in renal transplant recipients is essential for the proper evaluation and management of these important disorders. This review outlines the pathogenesis, diagnostic workup, and therapeutic rationale for diabetes and hypertension after transplantation.
ISSN:	1534-4827 1539-0829
DOI:	10.1007/s11892-008-0038-6