Snare-assisted flexible endoscope in trans-gastric endoscopic gallbladder-preserving surgery: A pilot animal study

Natural orifice transluminal endoscopic surgery (NOTES) gallbladder-preserving surgery by flexible endoscopy is an emerging technology. However, the gallbladder fails to obtain traction and positioning functions during the operation. To evaluate the feasibility and safety of a new surgical method, &...

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Published in:World journal of gastroenterology : WJG Vol. 28; no. 19; pp. 2112 - 2122
Main Authors: Guo, Xian-Wen, Liang, Yun-Xiao, Huang, Peng-Yu, Liang, Lie-Xin, Zeng, Yi-Qing, Ding, Zhen
Format: Journal Article
Language:English
Published: United States Baishideng Publishing Group Inc 21-05-2022
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Summary:Natural orifice transluminal endoscopic surgery (NOTES) gallbladder-preserving surgery by flexible endoscopy is an emerging technology. However, the gallbladder fails to obtain traction and positioning functions during the operation. To evaluate the feasibility and safety of a new surgical method, "snare-assisted pure NOTES gallbladder-preserving surgery". Eight miniature pigs were randomly divided into the experimental group [NOTES gallbladder-preserving surgery using the snare device, snare assisted (SA)] and the control group (NOTES gallbladder-preserving surgery without using the snare device, NC), with four cases in each group. The differences between the two groups of animals in operating time, operating workload, complications, adverse events, white blood cells, and liver function were determined. No differences were found in the surgical success rate, gallbladder incision closure, white blood cell count, or liver function between the two groups. The total operating time, gallbladder incision blood loss, gallbladder disorientation time, gallbladder incision closure time, and workload scores on the National Aeronautics and Space Administration-Task Load Index were significantly reduced in the SA group ( < 0.05). These results indicated that snare-assisted pure NOTES gallbladder-preservation surgery using standard endoscopic instruments reduced the difficulty of operation, shortened operation time, and did not increase complications in pigs. A new method for pure NOTES gallbladder-preservation surgery was provided.
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Supported by National Natural Science Foundation of China, No. 82060104; and Construction of Guangxi Clinical Medical Research Center for Digestive Diseases, No. AD17129027.
Author contributions: Guo XW and Ding Z contributed equally to this work; Guo XW and Ding Z were responsible for the study concept and design, including endoscopic procedures; all authors conducted the endoscopic operations together; Guo XW drafted the manuscript; Ding Z revised and finalized the manuscript.
Corresponding author: Zhen Ding, PhD, Chief Doctor, Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. docd720@126.com
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v28.i19.2112