Synthesis of new heterocyclic derivatives of α,α-trehalose

Several novel N-1, N-2, and S-5 tetrazole and 1,3,4-oxadiazole derivatives of α,α-trehalose disubstituted at C-6,6′, with potential synthetic and pharmacological interest were prepared from commercial tetrazoles and 1,3,4-oxadiazoles in reaction with hexa- O-benzyl-6,6′-di- O-triflyl-α,α-trehalose....

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Bibliographic Details
Published in:	Carbohydrate research Vol. 343; no. 3; pp. 536 - 540
Main Authors:	Luduvico, Inácio, Couri, Mara R.C., dos Santos, Leandro J., Prado, Maria A.F., Freitas Gil, Rossimiriam P., Alves, Rosemeire B.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 25-02-2008
Subjects:	1,3,4-Oxadiazole Alkylation Heterocyclic Compounds - chemical synthesis Oxadiazoles Tetrazole Tetrazoles Trehalose - chemical synthesis α,α-Trehalose α,α-Trehalose 1,3,4-Oxadiazole Tetrazole Alkylation
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Summary:	Several novel N-1, N-2, and S-5 tetrazole and 1,3,4-oxadiazole derivatives of α,α-trehalose disubstituted at C-6,6′, with potential synthetic and pharmacological interest were prepared from commercial tetrazoles and 1,3,4-oxadiazoles in reaction with hexa- O-benzyl-6,6′-di- O-triflyl-α,α-trehalose.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0008-6215 1873-426X
DOI:	10.1016/j.carres.2007.11.019