The Effectiveness of Narrow Band Uvb (Nb-Uvb) In the Treatment of Pityriasis Lichenoides Chronica (PLC) In Vietnam

• Published in: Open access Macedonian journal of medical sciences Vol. 7; no. 2; pp. 221 - 223
• Main Authors: Huu, Doanh Le, Minh, Thao Ngo, Van, Thuong Nguyen, Minh, Phuong Pham Thi, Huu, Nghi Dinh, Cam, Van Tran, Huyen, My Le, Nguyet, Minh Vu, Thi, Mai Le, Thu, Hien Do Thi, Hau, Khang Tran, Gandolfi, Marco, Satolli, Francesca, Feliciani, Claudio, Tirant, Michael, Vojvodic, Aleksandra, Lotti, Torello
• Format: Journal Article
• Language: English
• Published: Macedonia Republic of Macedonia 30-01-2019
• Subjects: Clinical Science; NB-UVB; Effectiveness; Safety; Pityriasis lichenoides chronica; Phototherapy
• ISSN: 1857-9655; 1857-9655
• DOI: 10.3889/oamjms.2019.055

This prospective clinical study presents the experiences with NB-UVB monotherapy in the treatment of PLC on Vietnamese patients.
We enrolled at National Hospital of Dermatology and Venereology (NHDV), Vietnam, 29 PLC patients with generalised disease involving at least 60% of the total body surface (based on Nine's Rule) and/or failed to respond to other modalities of treatment. Patients were treated with NB-UVB followed the guideline of the psoriatic treatment of AAD-2010, three times weekly.
A complete response (CR) was seen in 24 out of 29 PLC patients (82.8%) with a mean cumulative dose of 9760.5 mJ/cm
after a mean treatment period of 4.6 weeks (13.8 ± 7.4 exposures). Mild side effects were observed: 69% erythema minimum, 55.2% irritation related to dry skin. No severe side effects were seen during the study. No relapses occurred in 24 CR patients within a mean period of 3 months after the last treatment.
NB-UVB therapy is an effective and safe option for the treatment and management of PLC.