Efficient highly stereoselective synthesis of olefinic macrocyclic crown-formazans with the Z-configuration via ring-closure metathesis

• Published in: Tetrahedron letters Vol. 43; no. 39; pp. 6971 - 6974
• Main Authors: Ibrahim, Yehia A, Behbehani, Haider, Ibrahim, Maher R, Abrar, Nada M
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 23-09-2002
• Subjects: 1,5-bis- o-allyloxyphenylformazans; 1,ω-dienes; dibenzo[ b, i]-1,11-dioxa-4,5,7,8-tetraazacyclopentadeca-2,4,6,9,13-pentaene; Grubbs’ catalyst; pyridine N-oxides; reduction; ring-closure metathesis; 1,ω-dienes; pyridine N-oxides; ring-closure metathesis; 1,5-bis- o-allyloxyphenylformazans; reduction; Grubbs’ catalyst; dibenzo[ b, i]-1,11-dioxa-4,5,7,8-tetraazacyclopentadeca-2,4,6,9,13-pentaene
• ISSN: 0040-4039; 1873-3581
• DOI: 10.1016/S0040-4039(02)01598-8

RCM of 1,5-bis-
o-allyloxyphenylformazans with the suitably located 1,ω-dienes leads to an efficient, highly stereoselective, synthetic approach towards
Z-olefinic 15-membered ring macrocyclic crown-formazans with potential applications. A novel reduction of pyridine
N-oxides to pyridines by the action of Grubbs’ catalyst has been discovered.
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