A useful acylation method using trichloroacetonitrile and triphenylphosphine for solid phase organic synthesis

A novel acylation procedure was developed for polymer supported synthesis, with in situ generated acyl chlorides using trichloroacetonitrile and triphenylphosphine. A new solid phase acylation method with in situ generated acyl chloride is described.

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Bibliographic Details
Published in:	Tetrahedron letters Vol. 43; no. 34; pp. 6039 - 6041
Main Authors:	Vágó, István, Greiner, István
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 19-08-2002
Subjects:	acyl chloride acylation solid phase synthesis acyl chloride acylation solid phase synthesis
Online Access:	Get full text
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Description
Summary:	A novel acylation procedure was developed for polymer supported synthesis, with in situ generated acyl chlorides using trichloroacetonitrile and triphenylphosphine. A new solid phase acylation method with in situ generated acyl chloride is described.
ISSN:	0040-4039 1873-3581
DOI:	10.1016/S0040-4039(02)01241-8