Thermokinetic analysis of the hydration process of calcium phosphate cement

• Published in: Journal of thermal analysis and calorimetry Vol. 85; no. 3; pp. 785 - 789
• Main Authors: GAO, W. Y, WANG, Y. W, DONG, L. M, YU, Z. W
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer 01-09-2006
• Subjects: Biological and medical sciences; Medical sciences; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Technology. Biomaterials. Equipments. Material. Instrumentation; rebuilding thermogenetic curve; Hydration; hydration process; Cement; calcium phosphate cement; Calcium phosphate; Biomaterial; Microcalorimetry; Thermokinetics
• ISSN: 1388-6150; 1588-2926; 1572-8943
• DOI: 10.1007/s10973-005-7433-x

A microcalorimeter (Setaram c-80) was used to study the thermokinetics of the hydration process of calcium phosphate cement (CPC), a biocompatible biomaterial used in bone repair. The hydration enthalpy was determined to be 35.8 J g at 37.0 deg C when up to 80 mg CPC was dissolved in 2 mL of citric buffer. In the present study, parameters related to time constants of the calorimeter were obtained by fitting the recorded thermal curves with the function theta=Ae(1- e). The real thermogenetic curves were then retrieved with Tian function and the transformation rate of the hydration process of CPC was found to follow the equation alpha=1-[1-(0.0075t)]. The microstructures of the hydrated CPC were examined by scanning electron microscopy. The nano-scale flake microstructures are due to crystallization of calcium phosphate and they could contribute to the good biocompatibility and high bioactivity.