Extraction yield and kinetic study of Lippia graveolens with supercritical CO2

• Published in: The Journal of supercritical fluids Vol. 145; pp. 205 - 210
• Main Authors: Soto-Armenta, Laura Catalina, Sacramento-Rivero, Julio C., Ruiz-Mercado, Claudia Araceli, Lope-Navarrete, Mariela Carolina, Rocha-Uribe, José Antonio
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-03-2019
• Subjects: Carvacrol; Essential oil; Lippia graveolens; Supercritical extraction with CO2; Thymol; Yield; Lippia graveolens; Supercritical extraction with CO2; Carvacrol; Essential oil; Yield; Thymol
• ISSN: 0896-8446; 1872-8162
• DOI: 10.1016/j.supflu.2018.12.018

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•First report of supercritical CO2 extraction (SFE) of Lippia graveolens leaves.•The best scCO2 conditions were 35.0 MPa and 60 °C.•Carvacrol was the majority compound in all the experiments.•Biological activity of carvacrol from oregano could promote future research.•A three extraction stages model fit very well the experimental yields.
In this study, leave extracts of Lippia graveolens were obtained using supercritical CO2. The objective was to evaluate the effect of temperature and pressure on the extraction yield and kinetics. Supercritical fluid extractions were performed at three pressures (13, 15 and 35 MPa) and two temperatures (40 and 60 °C). Sovová’s model for supercritical fluid extraction was fitted to describe the kinetic extraction curves and analyze the results. The extracts were analyzed by GC–MS, where Carvacrol was the majority compound in all the experiments. A maximum yield of 2.6% on a dry weight basis was obtained at 35 MPa and 60 °C. The extraction yield increased with temperature and pressure, in all the analyzed samples.