A novel asymmetric approach to a densely functionalized lactarane ring system through a domino ring opening–ring closing metathesis of a norbornene derivative

A novel asymmetric approach to a densely functionalized lactarane ring system through a domino ring opening–ring closing metathesis of a norbornene derivative

A novel route for the synthesis of a highly functionalized lactarane skeleton in enantiomerically pure form is described via ROM–RCM of an appropriately constructed norbornene derivative as the key step.

Saved in:
Bibliographic Details
Published in:Tetrahedron letters Vol. 49; no. 39; pp. 5649 - 5651
Main Authors: Mondal, Sujit, Malik, Chanchal K., Ghosh, Subrata
Format: Journal Article
Language:English
Published: Elsevier Ltd 22-09-2008
Subjects:
Aldol reaction
Metathesis
Stereocontrol
Terpenoids
Aldol reaction
Terpenoids
Metathesis
Stereocontrol
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A novel route for the synthesis of a highly functionalized lactarane skeleton in enantiomerically pure form is described via ROM–RCM of an appropriately constructed norbornene derivative as the key step.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2008.07.083