Epilepsy Surgery for Cognitive Improvement in Epileptic Encephalopathy

Epilepsy Surgery for Cognitive Improvement in Epileptic Encephalopathy

Epileptic encephalopathies are defined by the presence of frequent epileptiform activity that causes neurodevelopmental slowing or regression. Here, we review evidence that epilepsy surgery improves neurodevelopment in children with epileptic encephalopathies. We describe an example patient with epi...

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Bibliographic Details
Published in:Neurosurgery clinics of North America Vol. 35; no. 1; pp. 49 - 59
Main Authors: McLaren, John R, Kahle, Kristopher T, Richardson, R Mark, Chu, Catherine J
Format: Journal Article
Language:English
Published: United States 01-01-2024
Subjects:
Child
Cognition
Electroencephalography
Epilepsy - complications
Epilepsy - surgery
Humans
Interictal localization
Pediatric epilepsy surgery
Case report
CSWS
Outcome
Neurodevelopment
ESES
Developmental epileptic encephalopathy
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Description
Summary:Epileptic encephalopathies are defined by the presence of frequent epileptiform activity that causes neurodevelopmental slowing or regression. Here, we review evidence that epilepsy surgery improves neurodevelopment in children with epileptic encephalopathies. We describe an example patient with epileptic encephalopathy without drug refractory seizures, who underwent successful diagnostic and therapeutic surgeries. In patients with epileptic encephalopathy, cognitive improvement alone is a sufficient indication to recommend surgical intervention in experienced centers.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1042-3680
1558-1349
1558-1349
DOI:10.1016/j.nec.2023.08.002