Enhanced DNA libraries for methylation analysis

An efficient protocol for the preparation of DNA libraries for the analysis of methylation patterns in cell-free DNA in plasma enhances the sensitivity of bisulfite sequencing for the early detection of lung cancer.

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Bibliographic Details
Published in:	Nature biomedical engineering Vol. 5; no. 6; pp. 490 - 492
Main Author:	Haque, Imran S.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01-06-2021 Nature Publishing Group
Subjects:	631/61/514/2254 631/67/1612 692/53/2421 692/699/67/2322 Biomedical and Life Sciences Biomedical Engineering/Biotechnology Biomedicine Bisulfite Deoxyribonucleic acid DNA DNA methylation DNA sequencing Lung cancer Methylation News & Views news-and-views Sensitivity enhancement
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Description
Summary:	An efficient protocol for the preparation of DNA libraries for the analysis of methylation patterns in cell-free DNA in plasma enhances the sensitivity of bisulfite sequencing for the early detection of lung cancer.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Commentary-1
ISSN:	2157-846X 2157-846X
DOI:	10.1038/s41551-021-00750-9