Hypertension in the elderly:Are we all on the same wavelength?

Hypertension is of frequent occurrence in the elderly population.Isolated systolic hypertension(ISH) accounts for the majority of cases of hypertension in the elderly.ISH is associated with a 2-4-fold increase in the risk of myocardial infarction,left ventricular hypertrophy,renal dysfunction,stroke...

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Published in:World journal of cardiology Vol. 3; no. 8; pp. 263 - 266
Main Authors: Pant, Sadip, Neupane, Pritam, Ramesh, Khatri Chhetri, Barakoti, Murari
Format: Journal Article
Language:English
Published: United States Baishideng Publishing Group Co., Limited 26-08-2011
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Summary:Hypertension is of frequent occurrence in the elderly population.Isolated systolic hypertension(ISH) accounts for the majority of cases of hypertension in the elderly.ISH is associated with a 2-4-fold increase in the risk of myocardial infarction,left ventricular hypertrophy,renal dysfunction,stroke,and cardiovascular mortality.There have been many studies to determine the optimal treatment for hypertension in the elderly. Why,when and how to treat hypertension in the elderly was the scope of the majority of these trials.Despite countless efforts many aspects remain obscure.While a number of novel drugs are being developed,the issue of whether all antihypertensive drugs bestow parallel benefits or whether some agents offer a therapeutic advantage beyond blood pressure control remains of crucial importance.Furthermore,the response of theelderly to different antihypertensive agents also differs from that of younger patients and may explain some of the disparities in outcomes of trials conducted in elderly patients with hypertension.
Bibliography:Sadip Pant,Department of Internal Medicine,University of Arkansas for Medical Sciences,Little Rock,AR 72205,United States Pritam Neupane,Medical College of Georgia,Augusta,GA 30192,United States Khatri Chhetri Ramesh,Mercy Catholoc Medical Center,Darby,PA 19023,United States Murari Barakoti,Institute of Medicine,Maharajgunj,Ktm 20009,Nepal
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Correspondence to: Dr. Sadip Pant, MD, Department of Internal Medicine, University of Arkansas for Medical Sciences, 4301 W Markham, Little Rock, AR 72205, United States. sadippant@hotmail.com
Telephone: +1-757-2639290 Fax: +501-686-6001
Author contributions: Pant S and Neupane P designed the research; Pant S, Neupane P, Ramesh KC and Barakoti M performed the research; Pant S, Ramesh KC, Barakoti M contributed new reagents/analytic tools; Pant S, Neupane P, Ramesh KC and Barakoti M analyzed the data; and Pant S, Neupane P, Ramesh KC wrote the paper.
ISSN:1949-8462
1949-8462
DOI:10.4330/wjc.v3.i8.263