Predictors and Prognostic Significance of Troponin-I Release following Elective Coronary Angioplasty

• Published in: Journal of international medical research Vol. 34; no. 6; pp. 612 - 623
• Main Authors: Izgi, A, Tanalp, AC, Kirma, C, Dundar, C, Oduncu, V, Akcakoyun, M, Ozveren, O, Mutlu, B
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01-11-2006
• Subjects: Adult; Aged; Angioplasty - adverse effects; Elective Surgical Procedures - adverse effects; Female; Humans; Male; Middle Aged; Multivariate Analysis; Prognosis; Treatment Outcome; Troponin I - blood; Percutaneous coronary intervention; Coronary angioplasty; Long-term outcome; Ischaemic heart disease; Cardiac troponin-I
• ISSN: 0300-0605; 1473-2300
• DOI: 10.1177/147323000603400606

The objective of this study was to investigate the predictors and prognostic significance of post-procedural cardiac troponin (cTn)-I elevations in a consecutive series of patients who underwent elective percutaneous coronary intervention (PCI). cTn-I was measured in 100 patients immediately before and within 24 h after the elective PCI. Post-procedural cTn-I elevation was observed in 27 of the 100 patients. In multivariate analysis, basal haemoglobin values and the number of repeated balloon dilatations were found to be independent predictors of cTn-I elevation. During the follow-up period of 12 ± 1.2 months, the cTn-I-positive group had more major adverse cardiovascular events than the cTn-I-negative group (33.3% versus 16.4%, respectively), but the difference was not significant. An increase in cTn-I levels following elective PCI procedures was frequent but did not predict a poor long-term outcome.