TI-201 SPECT in Pseudotumoral Multiple Sclerosis
A patient with multiple sclerosis had a pseudotumoral plaque evident on a brain MRI that was indistinguishable from a malignant brain tumor. TI-201 SPECT showed uptake of TI-201 in the lesion with indices of 1.55 and 1.96 at 30 minutes and 3 hours, respectively. The retention index was 26.4%. The pa...
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| Published in: | Clinical nuclear medicine Vol. 24; no. 3; pp. 186 - 188 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Philadelphia, PA
Lippincott Williams & Wilkins, Inc
01-03-1999
Hagerstown, MD Lippincott |
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| Abstract | A patient with multiple sclerosis had a pseudotumoral plaque evident on a brain MRI that was indistinguishable from a malignant brain tumor. TI-201 SPECT showed uptake of TI-201 in the lesion with indices of 1.55 and 1.96 at 30 minutes and 3 hours, respectively. The retention index was 26.4%. The patient had clinical and radiologic spontaneous improvement, and the results of TI-201 SPECT performed 3 months later were negative. TI-201 uptake in multiple sclerosis pseudotumoral plaques has not been described before. In this patient, TI-201 SPECT could not differentiate a large multiplesclerosis plaque from a malignant brain tumor. |
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| AbstractList | A patient with multiple sclerosis had a pseudotumoral plaque evident on a brain MRI that was indistinguishable from a malignant brain tumor. TI-201 SPECT showed uptake of TI-201 in the lesion with indices of 1.55 and 1.96 at 30 minutes and 3 hours, respectively. The retention index was 26.4%. The patient had clinical and radiologic spontaneous improvement, and the results of TI-201 SPECT performed 3 months later were negative. TI-201 uptake in multiple sclerosis pseudotumoral plaques has not been described before. In this patient, TI-201 SPECT could not differentiate a large multiplesclerosis plaque from a malignant brain tumor. |
| Author | OBACH, VICTOR GONZALEZ-MENACHO, JORDI GRAUS, FRANCESC VIDAL, SERGI LOMEÑA, FRANCESC |
| AuthorAffiliation | From the Service of Neurology and Nuclear Medicine,† Hospital Clinic, University of Barcelona, Barcelona, Spain |
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| Cites_doi | 10.1007/BF00285584 10.1007/BF02261244 10.1007/BF00168874 |
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| Keywords | Radionuclide study Pseudotumor Thallium Nervous system diseases Multiple sclerosis Central nervous system Nuclear magnetic resonance imaging Photon Differential diagnostic Inflammatory disease Case study Central nervous system disease Distribution Medical imagery Tumor Emission tomography |
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| References | Yoshii (R1-11-20110409) 1993; 20 Dierckx (R2-11-20110409) 1994; 21 Ueda (R3-11-20110409) 1993; 20 |
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| SubjectTerms | Biological and medical sciences Brain - diagnostic imaging Brain Neoplasms - diagnostic imaging Diagnosis, Differential Humans Male Medical sciences Middle Aged Multiple Sclerosis - diagnostic imaging Neurology Thallium Radioisotopes Tomography, Emission-Computed, Single-Photon Tumors of the nervous system. Phacomatoses |
| Title | TI-201 SPECT in Pseudotumoral Multiple Sclerosis |
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