Single crystal X-ray structurally characterized palladium(II) selective fluorescence and colorimetric indicator for human breast cancer cell imaging

• Published in: Inorganica Chimica Acta Vol. 436; pp. 52 - 56
• Main Authors: Ghosh, Abhijit, Nandi, Sandip, Sengupta, Archya, Chattopadhyay, Ansuman, Lohar, Sisir, Das, Debasis
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01-09-2015
• Subjects: Fluorescence; Hydrolysis; Naked eye; Palladium; Rhodamine b; Single crystal X-ray structure; Hydrolysis; Fluorescence; Single crystal X-ray structure; Naked eye; Palladium; Rhodamine b
• ISSN: 0020-1693; 1873-3255
• DOI: 10.1016/j.ica.2015.07.015

4-Benzonitrile appended rhodamine B hydrazide derivative (RDHDNB) selectively detects Pd2+ both naked eye and under UV light. Moreover, RDHDNB easily detects Pd2+ in human breast cancer cells MCF7, under normal and fluorescence microscope. [Display omitted]
•Visible light excitable, single crystal X-ray structurally characterized Pd2+ selective fluorescence probe.•Lowest detection limit for 5.7×10−8M.•RDHDNB is useful to detect Pd2+ in human breast cancer cells MCF7, under normal and fluorescence microscope.•First report on Pd2+ assisted hydrolysis of a rhodamine based probe for colorimetric and fluorescence detection.•Common ions do not interfere.
Condensation of rhodamine B hydrazide with 4-formylbenzonitrile generates a Pd2+ selective probe (RDHDNB) that allows its naked eye and fluorescence recognition. Moreover, RDHDNB is useful to detect Pd2+ in human breast cancer cells MCF7, under normal and fluorescence microscope.