Doppler ultrasonographic evaluation of renal arterial resistive and pulsatility indices in overhydrated Beagles

• Published in: American journal of veterinary research Vol. 75; no. 4; pp. 344 - 348
• Main Authors: Lee, Seungjun, Park, Nohwon, Kim, Jaehwan, Eom, Ki-Dong
• Format: Journal Article
• Language: English
• Published: United States 01-04-2014
• Subjects: Animals; Dogs - physiology; Female; Kidney - blood supply; Kidney - diagnostic imaging; Male; Pulsatile Flow; Regional Blood Flow; Renal Artery - physiology; Sodium Chloride - administration & dosage; Ultrasonography, Doppler - veterinary; Vascular Resistance - physiology
• ISSN: 0002-9645; 1943-5681
• DOI: 10.2460/ajvr.75.4.344

To determine renal arterial resistive index (RI) and pulsatility index (PI) and clinical signs of overhydration induced by IV administration of saline (0.9% NaCl) solution and to assess RI and PI as variables for monitoring of dogs to detect overhydration.
10 clinically normal Beagles.
Each dog received saline solution at a maintenance rate (2.5 mL/kg/h) and a rate 3 times that of the maintenance rate (overhydration rate; 7. 5 mL/kg/h). Values of RI and PI were determined with pulsed-wave Doppler ultrasonographic examination of renal interlobar or arcuate arteries before saline solution administration, every hour during 5 hours of administration, and 1 hour after administration was stopped.
No significant changes in RI or PI were detected during administration of saline solution at the maintenance rate. However, RI (starting 1 hour after the beginning of fluid administration [mean ± SD value, 0.589 ± 0.012]) and PI (starting 2 hours after the beginning of fluid administration [value, 0.867 ± 0.052]) were significantly lower during administration at the overhydration rate than they were during administration at the maintenance rate. Clinical signs of overhydration were observed in all dogs starting 4 hours after the beginning of fluid administration at the overhydration rate.
Results indicated overhydration of dogs caused significant decreases in RI and PI prior to detection of clinical signs of overhydration. Ultrasonographic determination of renal arterial RI and PI seemed to be a noninvasive and sensitive method for evaluation of overhydration in dogs.