The Role of Robot-Assisted Radical Prostatectomy in High-Risk Prostate Cancer

• Published in: Journal of endourology Vol. 31; no. 3; p. 229
• Main Authors: Srougi, Victor, Tourinho-Barbosa, Rafael R, Nunes-Silva, Igor, Baghdadi, Mohammed, Garcia-Barreras, Silvia, Rembeyo, Gregory, Eiffel, Sophie S, Barret, Eric, Rozet, Francois, Galiano, Marc, Sanchez-Salas, Rafael, Cathelineau, Xavier
• Format: Journal Article
• Language: English
• Published: United States 01-03-2017
• Subjects: Humans; Lymph Node Excision - methods; Lymphatic Metastasis - diagnosis; Male; Prostatectomy - adverse effects; Prostatectomy - methods; Prostatic Neoplasms - pathology; Prostatic Neoplasms - surgery; Robotic Surgical Procedures - methods; Survival Analysis; Treatment Outcome; prostatectomy; prostate cancer; locally advanced; robot-assisted radical prostatectomy; robotic; high risk
• ISSN: 1557-900X
• DOI: 10.1089/end.2016.0659

Prostate cancer (PCa) is stratified into different risk categories based on the patient's prognosis. High-risk disease was formerly characterized by an increased risk of metastasis and lethality, requiring complex treatments. Surgery was recently highlighted to have a pivotal role for the treatment of such cases, even as monotherapy. In the past, open radical prostatectomy was performed for most patients with high-risk PCa; however, robot-assisted radical prostatectomy (RARP) emerged as a reasonable option because it provided optimal outcomes for low- and intermediate-risk PCa. Robust studies are lacking to properly assess the role of RARP for high-risk PCa. We summarize this knowledge and present a literature review on the perioperative recovery and functional and oncologic outcomes of RARP for the treatment of patients with high-risk PCa.