Transformations of anilides of 3-aryl-2,3-epoxypropionic acids when exposed to acidic agents

• Published in: Russian chemical bulletin Vol. 64; no. 12; pp. 2857 - 2864
• Main Authors: Mamedov, V. A., Mamedova, V. L., Khikmatova, G. Z., Samigullina, A. I., Gubaidullin, A. T., Bazanova, O. B., Rizvanov, I. Kh, Sinyashin, O. G.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01-12-2015
• Subjects: Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Full Articles; Inorganic Chemistry; Organic Chemistry; ones; anilides of 3-bromo-2-hydroxy-3-arylpropionic acids; anilides of 3-aryl-2,3-epoxypropionic acids; X-ray diffraction analysis; quinolin-2
• ISSN: 1066-5285; 1573-9171
• DOI: 10.1007/s11172-015-1238-2

Anilides of 3-aryl-2,3-epoxypropionic acids on treatment with aqueous HBr gave 3-aryl-3-bromo-2-hydroxypropionic acid anilides and (in some cases) 2-bromo-3-hydroxy regioisomers. Cyclization of these products into 3-arylquinolin-2(1
H
)-ones was studied.