New (S)-proline derivatives as catalysts for the enantioselective aldol reaction

New (S)-proline derivatives as catalysts for the enantioselective aldol reaction

(2S)-N- 2-[(R)-Hydroxy(phenyl)methyl]phenyl pyrrolidine-2-carboxamide, (2 S) - N -{2-[( S )-hydroxy(phenyl)methyl]phenyl}pyrrolidine-2-carboxamide, and ( S )- N -{2-[hydroxy-(diphenyl)methyl]phenyl}pyrrolidine-2-carboxamide were obtained and tested as catalysts for an asymmetric aldol reaction of 4-...

Full description

Saved in:
Bibliographic Details
Published in:Russian chemical bulletin Vol. 58; no. 9; pp. 1903 - 1907
Main Authors: Maleev, V. I., Gugkaeva, Z. T., Moskalenko, M. A., Tsaloev, A. T., Lyssenko, K. A.
Format: Journal Article
Language:English
Published: Boston Springer US 01-09-2009
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Full Articles
Inorganic Chemistry
Organic Chemistry
organocatalysis
proline
(
aldol reaction
Keywords
asymmetric synthesis
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:(2S)-N- 2-[(R)-Hydroxy(phenyl)methyl]phenyl pyrrolidine-2-carboxamide, (2 S) - N -{2-[( S )-hydroxy(phenyl)methyl]phenyl}pyrrolidine-2-carboxamide, and ( S )- N -{2-[hydroxy-(diphenyl)methyl]phenyl}pyrrolidine-2-carboxamide were obtained and tested as catalysts for an asymmetric aldol reaction of 4-nitrobenzaldehyde with acetone.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-009-0259-0