Suspected Buprenorphine-Precipitated Opioid Withdrawal following Intercourse: A Case Report
Buprenorphine, a partial mu-opioid receptor agonist, is a commonly prescribed medication for opioid use disorder (OUD). There is evidence that drugs may enter the male genitourinary tract by an ion-trapping process, based on the lipid solubility and degree of ionization (1). While little is known ab...
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| Published in: | Journal of pain & palliative care pharmacotherapy Vol. 37; no. 4; pp. 314 - 316 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
02-10-2023
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| Online Access: | Get full text |
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| Summary: | Buprenorphine, a partial mu-opioid receptor agonist, is a commonly prescribed medication for opioid use disorder (OUD). There is evidence that drugs may enter the male genitourinary tract by an ion-trapping process, based on the lipid solubility and degree of ionization (1). While little is known about the pharmacokinetics of drugs in seminal fluid, pH is thought to play an integral role. Limited evidence exists surrounding cervical absorption of drugs via seminal fluid transmission. This also prompts survey of the frequency of this event and the influence on treatment within this population. |
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| Bibliography: | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 |
| ISSN: | 1536-0288 1536-0539 |
| DOI: | 10.1080/15360288.2023.2250344 |